PFUPISO UYE TSANANGURO MUYEdzo
M.pneumoniae inogona kukonzera zviratidzo zvakawanda zvakadai semabayo ekutanga atypical, tracheobronchitis, uye chirwere chepamusoro chekufema.Tracheobronchitis inonyanya kuwanda muvana vane immune system yakaderedzwa, uye kusvika ku18% yevana vane hutachiona vanoda kuchipatara.Mumakiriniki, M. pneumoniae haigoni kusiyaniswa kubva kune pneumonia inokonzerwa nemamwe mabhakitiriya kana mavhairasi.Kuongororwa kwakananga kwakakosha nokuti kurapwa kweM. pneumoniae utachiona ne β-lactam antibiotics hakubatsiri asi kurapwa nemacrolides kana tetracyclines kunogona kuderedza nguva yechirwere.
Kunamatira kweM. pneumoniae kune epithelium yekufema ndiyo danho rekutanga muhutano hwehutachiona.Iyi yekubatanidza chiitiko chiitiko chakaoma chinoda akati wandei adhesin mapuroteni, akadai seP1, P30, uye P116.Chiitiko chechokwadi cheM. pneumoniae chinosanganiswa nehutachiona hachina kujeka sezvo zvakaoma kuongorora mumatanho ekutanga ehutachiona.
PRINCIPLE
Mycoplasma Pneumoniae IgG/IgM Rapid Test Kit zvichibva pamusimboti we qualitative immunochromatographic assay yekuziva Mycoplasma Pneumoniae IgG/IgM masoja ekudzivirira chirwere ari muserum yevanhu, plasma kana ropa rose. magedhi), 2) nitrocellulose membrane strip ine test band (T bhendi) uye bhandi rekutonga (C bhendi).Iyo T bhendi yakashongedzwa nembeva inorwisa-munhu IgG antibody, uye C bhendi rakafanoputirwa nembudzi anti-mbeva IgG antibody.Strip B ine: 1) burgundy colored conjugate pad ine MP antigen yakasanganiswa negoridhe colloid (MP Antigen conjugates), 2) nitrocellulose membrane strip ine test bhendi (T bhendi) uye control bhendi (C bhendi).Iyo T bhendi yakashongedzwa nembeva inorwisa-munhu IgM antibody, uye C bhendi rakafanoputirwa nembudzi anti-mbeva IgG antibody.
Strip A: Kana huwandu hwakakwana hwebvunzo hwemuenzaniso hwaiswa mumuenzaniso tsime rebvunzo kaseti, mufananidzo wacho unotama necapillary chiito pakaseti.MP IgG antibody kana iripo mumuenzaniso inosunga kuMP Antigen conjugates.Iyo immunocomplex inozobatwa pa membrane neiyo pre-yakavharwa Mouse anti-human IgG antibody, ichigadzira burgundy yemavara T bhendi, ichiratidza MP IgG yakanaka bvunzo mhedzisiro.Kusavapo kweT band kunoratidza mhedzisiro yakaipa.Muedzo une mukati mekutonga (C bhendi) iyo inofanirwa kuratidza burgundy yemavara bhendi ye immunocomplex yembudzi anti-mouse IgG/mouse IgG-goridhe conjugate zvisinei nekuvepo kwemavara T bhendi.Zvikasadaro, mhedzisiro yebvunzo haishande uye mufananidzo unofanirwa kuongororwa nemumwe mudziyo.
Strip B: Kana huwandu hwakakwana hwebvunzo hwemuenzaniso hwaiswa mumuenzaniso tsime rebvunzo kaseti, mufananidzo wacho unotama necapillary chiito pakaseti.MP IgM antibody kana iripo mumuenzaniso inosunga kuMP Antigen conjugates.Iyo immunocomplex inozobatwa pa membrane ne pre-coated Mouse anti-human IgM antibody, ichigadzira burgundy yemavara T bhendi, ichiratidza MP IgM yakanaka bvunzo mhedzisiro.Kusavapo kweT band kunoratidza mhedzisiro yakaipa.Muedzo une mukati mekutonga (C bhendi) iyo inofanirwa kuratidza burgundy yemavara bhendi ye immunocomplex yembudzi anti-mouse IgG/mouse IgG-goridhe conjugate zvisinei nekuvepo kwemavara T bhendi.Zvikasadaro, mhedzisiro yebvunzo haishande uye mufananidzo unofanirwa kuongororwa nemumwe mudziyo.
