Tsanangudzo yakadzama
Nzira yekuona I yesyphilis
Kuonekwa kweTreponema pallidum IgM antibody
Kuonekwa kweTreponema pallidum IgM antibody inzira itsva yekuongorora njovhera mumakore achangopfuura.IgM antibody imhando ye immunoglobulin, ine zvakanakira zvekunzwa kwakanyanya, kuongororwa kwekutanga, uye kutsunga kuti chibereko chine utachiona hweTreponema pallidum.Kugadzirwa kweakananga IgM masoja ekudzivirira chirwere ndiyo yekutanga humoral immune immune yemuviri mushure mekutapukirwa nesyphilis nemamwe mabhakitiriya kana mavhairasi.Inowanzova yakanaka panguva yekutanga yehutachiona.Inowedzera nekukura kwechirwere, uyezve IgG antibody inosimuka zvishoma nezvishoma.
Mushure mekurapa kunoshanda, IgM antibody yakanyangarika uye IgG antibody yakaramba iripo.Mushure mekurapwa kwepenicillin, TP IgM yakanyangarika mudanho rekutanga syphilis varwere vane TP IgM yakanaka.Mushure mekurapa penicillin, varwere veTP IgM vane syphilis yechipiri vakanyangarika mukati memwedzi miviri kusvika ku8.Pamusoro pezvo, kuonekwa kweTP IgM kwakakosha zvikuru pakuongororwa kwecongenital syphilis muvana vachangozvarwa.Nekuti iyo IgM antibody molecule yakakura, amai IgM antibody haigone kupfuura nepa placenta.Kana TP IgM iri positive, mwana anenge aine utachiona.
Syphilis yekuona nzira II
Molecular biological kuonekwa
Mumakore achangopfuura, molecular biology yakagadzira nekukurumidza, uye PCR tekinoroji yakashandiswa zvakanyanya mukuita kwekiriniki.Iyo inonzi PCR inonzi polymerase chain reaction, ndiko kuti, kukwidziridza zvakasarudzwa spirochete DNA sequences kubva kune zvakasarudzwa zvinhu, kuitira kuti iwedzere nhamba yezvakasarudzwa spirochete DNA makopi, izvo zvinogona kuita kuti zvionekwe nemaprobe chaiwo, uye kuvandudza chiyero chekuongorora.
Nekudaro, iyi nzira yekuyedza inoda marabhoritari ine mamiriro akanaka chose uye nyanzvi dzekirasi yekutanga, uye kune mashoma marabhoritari ane mwero wakadaro muChina parizvino.Kana zvisina kudaro, kana pane kusvibiswa, iwe uchaisa Treponema pallidum, uye mushure mekuwedzera kweDNA, pachava neEscherichia coli, izvo zvinokusuruvarisa.Mamwe makiriniki madiki anowanzo kutevedzera fashoni.Vanorembedza rudzi rwePCR rabhoritari uye vanodya nekunwa pamwe chete, izvo zvinogona chete kuzvinyengera.Muchokwadi, kuongororwa kwesyphilis hakudi PCR, asi kuongororwa kweropa.