Basic information
Product Name | Catalog | Type | Mugamuchiri/Mabviro | Usage | Applications | Epitope | COA |
HCV Core-NS3-NS5 fusion antigen | BMIHCV203 | Antigen | E.coli | Capture | CMIA,WB | / | Download |
HCV Core-NS3-NS5 fusion antigen | BMIHCV204 | Antigen | E.coli | Conjugate | CMIA,WB | / | Download |
HCV Core-NS3-NS5 fusion antigen-Bio | BMIHCVB02 | Antigen | E.coli | Conjugate | CMIA,WB | / | Download |
HCV Core-NS3-NS5 fusion antigen | BMIHCV213 | Antigen | HEK293 Sero | Conjugate | CMIA,WB | / | Download |
Pathogenesis yehepatitis C haisati yanyatsojeka.Kana HCV ichidzokorora mumasero echiropa, inokonzera kuchinja kwemaitiro uye kushanda kwemasero echiropa kana kukanganisa kuumbwa kwechiropa cheprotein, izvo zvinogona kukonzera kupera uye necrosis yemasero echiropa, zvichiratidza kuti HCV inokuvadza zvakananga chiropa uye inoita basa mune pathogenesis.Nekudaro, vazhinji ve masvomhu vanotenda kuti cellular immunopathological reaction inogona kuita basa rakakosha.Vakaona kuti hepatitis C, senge hepatitis B, ine maCD3+ anopinda mukati mematishu ayo.Cytotoxic T masero (TC) anonyanya kurwisa masero anotarirwa ehutachiona hweHCV, izvo zvinogona kukonzera kukuvara kwesero rechiropa.
RIA kana ELISA
Radioimmunodiagnosis (RIA) kana enzyme-yakabatana immunosorbent assay (ELISA) yakashandiswa kuona anti HCV muserum.Muna 1989, Kuo et al.yakagadzira nzira yeradioimmunoassay (RIA) yekurwisa-C-100.Gare gare, Ortho Company yakabudirira kugadzira enzyme-yakabatana immunosorbent assay (ELISA) kuona anti-C-100.Nzira mbiri idzi dzinoshandisa recombinant yeast yakaratidza virus antigen (C-100-3, puroteni yakavharwa neNS4, ine 363 amino acids), mushure mekucheneswa, inoputirwa nemaburi madiki eplastic plate, yobva yawedzerwa neserum yakaedzwa.Iyo antigen yehutachiona inosanganiswa ne-anti-C-100 muserum yakaedzwa.Pakupedzisira, isotope kana enzyme yakanyorwa mbeva anti human lgG monoclonal antibody inowedzerwa, uye iyo substrate inowedzerwa kuti itarise ruvara.